患有良性发性位置性的患者的维生素D和尿酸状况低
Yuan-Yuan Ren1, Yan-Jun Wang1, Jin-Lan Li1
1Department of Otorhinolaryngology Head & Neck Surgery, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China.
Science progress
|October 9, 2023
概括
良性发性位置性 (BPPV) 与维生素D缺乏和尿酸水平降低有关. 低尿酸和维生素D缺乏的老年人可能面临患BPPV的更高风险.
科学领域:
- 内分泌学 在内分泌学.
- 神经学 神经学
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
背景情况:
- 良性性发性位置性 (BPPV) 是一种与耳相关的前庭神经障碍.
- 新出现的证据表明,维生素D和尿酸代谢在BPPV病变发生过程中起着作用.
研究的目的:
- 为了研究血清25-基维生素D (25(OH) D) 和尿酸水平在BPPV患者.
- 为了确定与BPPV相关的风险因素.
主要方法:
- 一项涉及182名BPPV患者和182名匹配对照者的病例控制研究.
- 对人口统计数据,体重指数,血压,血清,OH) D和尿酸水平的分析.
主要成果:
- BPPV显示女性占主导地位,平均年龄为60岁.
- 在BPPV患者和对照人群之间,25(OH) D水平没有显著差异,尽管BPPV患者的维生素D缺乏率较高.
- 尿酸水平在BPPV患者中明显较低;年龄和尿酸被确定为风险预测因素.
结论:
- 在BPPV患者中观察到维生素D水平较低,但25(OH) D水平与对照组没有显著差异.
- 高龄,维生素D缺乏和尿酸水平低是BPPV的潜在危险因素.
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