儿童多发性硬化症的体力活动和功能限制:疲劳和抑郁是混变量吗?
E Morghen Sikes1, Marcia Finlayson2, Brenda Banwell3
1Division of Occupational Therapy, Shenandoah University, Leesburg, VA, USA.
Journal of pediatric rehabilitation medicine
|October 9, 2023
概括
患有儿科多发性硬化症 (MS) 的年轻人体力活动与较少的日常生活限制有关. 即使考虑疲劳和抑郁症时,这种关联仍然很重要.
科学领域:
- 神经学 神经学
- 儿科健康 儿科健康
- 康复医学 康复医学 康复医学
背景情况:
- 儿科发病多发性硬化症 (MS) 对青少年提出了独特的挑战,影响了日常活动.
- 功能限制是一个常见的问题,影响生活质量.
- 身体活动在缓解这些限制方面的作用需要进一步研究,特别是关于混因素.
研究的目的:
- 调查中度至强度体力活动 (MVPA) 与儿科MS中的功能限制之间的关系.
- 为了确定疲劳和抑郁是否混了MVPA与该人群中的功能限制之间的关联.
主要方法:
- 从三个观察性研究中分析了来自65例儿科多发性硬化症病例 (年龄为16±1.7) 的数据.
- 收集了MVPA,功能限制,疲劳和抑郁症的自我报告措施.
- 使用统计分析,包括相关性和回归来检查关联.
主要成果:
- MVPA与功能限制 (r=0.45),疲劳 (r=-0.28) 和抑郁 (r=-0.32) 有显著的相关性.
- 功能限制与疲劳 (r=-0.45) 和抑郁症状 (r=-0.53) 密切相关.
- 在控制疲劳和抑郁症后,MVPA仍然与功能限制有显著的相关性 (β=0.27,p=0.04).
结论:
- 中度至强度的体力活动独立地与儿童多发性硬化症患者的年轻人感知到的功能限制有关.
- 这些发现表明,促进体育活动可能有助于减少功能限制,无论疲劳和抑郁症状.
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