转录因子HIF2α参与了急性髓性白血病的分化阻断

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Daniela Magliulo1, Matilde Simoni1, Carolina Caserta2

  • 1Division of Experimental Oncology, IRCCS San Raffaele Scientific Institute, Milan, Italy.

EMBO molecular medicine
|October 9, 2023
PubMed
概括

缺氧诱导因子2α (HIF2α) 通过阻断骨髓分化,驱动急性髓性白血病 (AML) 的进展. 抑制HIF2α与全转网红酸 (ATRA) 一起促进白血病细胞成熟.

关键词:
在AML,AML就是AML.亚特拉 亚特拉 亚特拉如果HIF2α差异化疗法是一种差异化疗法.

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