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Updated: Jul 14, 2025

Chemical Inactivation of the E3 Ubiquitin Ligase Cereblon by Pomalidomide-based Homo-PROTACs
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从基于博尔特佐米布的疗法向IRd的类型过渡是新诊断的多发性骨髓瘤的有效方法

Robert M Rifkin1, Caitlin L Costello2, Ruemu E Birhiray3

  • 1Rocky Mountain Cancer Centers/US Oncology Research, Denver, CO 80218, USA.

Future oncology (London, England)
|October 9, 2023
PubMed
概括

在博特佐米布诱导后切换到ixazomib-lenalidomide-dexamethasone (IRd) 改善了多发性骨髓瘤治疗反应和持续时间,而不是继续治疗博特佐米布.

关键词:
在课堂上进行过渡.伊克萨佐米比 (Ixazomib) 是一种药物.口服治疗是一种口服疗法.蛋白酶体抑制剂是一种蛋白酶体抑制剂.

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