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Updated: Jul 14, 2025

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NRF3抑制状癌发生,涉及到未折叠的蛋白质反应调节器HSPA5

Selina Gurri1, Beat Siegenthaler1, Michael Cangkrama1

  • 1Department of Biology, Institute of Molecular Health Sciences, ETH Zurich, Zurich, Switzerland.

EMBO molecular medicine
|October 9, 2023
PubMed
概括

转录因子NRF3作为皮肤瘤抑制剂. 它的缺失通过增加HSPA5水平促进皮肤癌的进展,这表明HSPA5抑制是潜在的治疗策略.

关键词:
在HSPA5中使用HSPA5.在NRF3中,NRF3是指NRF3.恶性瘤是一种恶性瘤.皮肤致癌的发生.不折叠的蛋白质反应反应

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