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Updated: Jul 14, 2025

A Familial Hypercholesterolemia Human Liver Chimeric Mouse Model Using Induced Pluripotent Stem Cell-derived Hepatocytes
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通过全基因组测序和机器学习,寻找与家族高胆固醇血现象型相关的新基因

D E Ivanoshchuk1, A B Kolker2, O V Timoshchenko3

  • 1Institute of Internal and Preventive Medicine - Branch of the Institute of Cytology and Genetics of the Siberian Branch of the Russian Academy of Sciences, Novosibirsk, Russia Institute of Cytology and Genetics of the Siberian Branch of the Russian Academy of Sciences, Novosibirsk, Russia.

Vavilovskii zhurnal genetiki i selektsii
|October 9, 2023
PubMed
概括

在家族性高胆固醇血症 (FH) 研究中,在PLD1,SIDT1,LRP1B和CETP基因中发现了新的遗传变异. 这些发现扩大了我们对常见基因突变缺席时FH原因的理解.

关键词:
在CETP的基础上.在LRP1B中,LRP1B是LRP1B.PLD1 PLD1 PLD1 PLD1 PLD1 PLD1 PLD1 PLD1 PLD1 PLD1在SIDT1的位置上.家庭性高胆固醇血症是什么机器学习是机器学习.进行全基因组测序.

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