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Updated: Jul 14, 2025

Using Next Generation Sequencing to Identify Mutations Associated with Repair of a CAS9-induced Double Strand Break Near the CD4 Promoter
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Published on: March 31, 2022

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双链DNA断裂修复:分子机制和治疗点

Jinpeng Tan1,2, Xingyao Sun1,2, Hongling Zhao2

  • 1Hengyang Medical College University of South China Hengyang Hunan Province China.

MedComm
|October 9, 2023
PubMed
概括

在放射治疗中,DNA双链断裂 (DSB) 是至关重要的. 本综述涵盖了DSB修复通路,MRN和DNA-PK等关键蛋白,以及针对癌症治疗的抑制剂.

关键词:
DSB维修服务提供者人力资源部的人力资源部Ku70/80异构体/DNAPKcs (DNAPK) 是一个一个复杂的MRN.这就是NHEJJ.治疗目标 治疗目标

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