在COVID-19患者中,与核酸转阴性时间相关的症状?
Qiang Li1, Lei Zhang2, Limin Feng1
1Second Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, China.
概括
对于2019年冠状病毒病 (COVID-19) 患者的Omicron变种,便秘,发烧和吐延长了核酸转阴性时间. 对这些传统中医 (TCM) 症状进行基于症状的治疗可能有助于恢复.
科学领域:
- 综合医学是一个整体的医学.
- 传染性疾病 传染性疾病
- 病毒学 病毒学
背景情况:
- 冠状病毒疾病2019 (COVID-19) 由SARS-CoV-2病毒引起,特别是Omicron变种,呈现出各种不同的临床表现.
- 传统中医 (TCM) 提供了一种整体的症状管理方法.
- 了解TCM症状与病毒清除之间的关系对于优化患者护理至关重要.
研究的目的:
- 为了调查特定的传统中医 (TCM) 症状与病毒核酸变为负的时间之间的关联,在COVID-19患者中感染了Omicron变种.
- 为了识别可能延长病毒分泌期的关键TCM症状.
主要方法:
- 一项涉及189名COVID-19患者 (年龄20至90岁) 携带Omicron变种的回顾性横截面研究.
- 采用多种线性回归模型来分析TCM症状对核酸转阴性时间的影响,控制诸如年龄,性别,高血压,糖尿病和冠心病等混变量.
主要成果:
- 观察到的最常见的TCM症状是咳,喉干燥,吐,发烧,喉痛,喉发,鼻水和鼻塞.
- 回归分析表明,便秘,发烧和吐与延长的核酸转阴性时间有显著的关联.
- 整体模型解释了12.3%的转向负时间变异 (调整后的R2=0.123).
结论:
- 便秘,发烧和吐被确定为关键的TCM症状,与Omicron变异COVID-19患者的延长病毒清除相关.
- 针对这些特定症状的有针对性的治疗策略在管理COVID-19恢复方面可能具有临床意义.
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