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Updated: Jul 14, 2025

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增强的TrkA信号损害了基础前脑依赖的行为

Laura Calvo-Enrique1,2, Silvia Lisa1,2, Cristina Vicente-García1,2

  • 1Department of Cell Biology and Pathology, Instituto de Neurociencias de Castilla y León (INCyL), Universidad de Salamanca, Salamanca, Spain.

Frontiers in molecular neuroscience
|October 9, 2023
PubMed
概括

增强神经生长因子 (NGF) /TrkA在基础前脑胆协神经元 (BFCNs) 中的信号传递影响神经元发育和认知功能. 均衡的NGF/TrkA信号传递对于中枢神经系统 (CNS) 中胆性系统的正常功能至关重要.

关键词:
NGF (神经生长因子)这就是TrakA的意思.基本前脑的前脑.胆固醇神经元是一种神经元.学习学习学习学习学习学习小鼠的行为行为.

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Enzyme-linked receptors are proteins that act as both receptor and enzyme, activating multiple intracellular signals. This is a large group of receptors that include the receptor tyrosine kinase (RTK) family. Many growth factors and hormones bind to and activate the RTKs.
Neurotrophin (NT) receptors are a family of RTKs, including trkA, trkB, and trkC (tropomyosin-related kinase) receptors. TrkA is specific for nerve growth factor (NGF), neurotrophin-6, and neurotrophin-7. TrkB binds...
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