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Updated: Jul 14, 2025

Analysis of RNA Processing Reactions Using Cell Free Systems: 3' End Cleavage of Pre-mRNA Substrates in vitro
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Analysis of RNA Processing Reactions Using Cell Free Systems: 3' End Cleavage of Pre-mRNA Substrates in vitro

Published on: May 3, 2014

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在NMD目标的成熟过程中经历了死化,并在衰变过程中经历了内核解裂

Marcus J Viscardi1, Joshua A Arribere1

  • 1Department of Molecular, Cellular and Developmental Biology, University of California at Santa Cruz, Santa Cruz, CA, USA.

bioRxiv : the preprint server for biology
|October 9, 2023
PubMed
概括

细胞通过使用无意中介的mRNA衰变 (NMD) 提前停止编码子降解有害的mRNA. 这项研究表明,NMD主要使用SMG-6依赖的内核分解裂变,而不是死乙烯化,来攻击这些mRNA.

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