2022mpox疫情的分子流行病学,传播和临床特征:2022mpox疫情的分子流行病学,传播和临床特征:系统审查
Nadim Sharif1, Nazmul Sharif2, Khalid J Alzahrani3
1Department of Microbiology Jahangirnagar University Savar Dhaka Bangladesh.
Health science reports
|October 9, 2023
概括
2022年Mopox疫情主要影响与男性发生性关系的男性,通过直接接触传播到全球. 本综述综合了mopox流行病学,临床特征和传播动态.
科学领域:
- 流行病学 流行病学
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 2022年mopox疫情在全球迅速蔓延,突出了对综合知识的需求.
- 在本次审查之前,对mopox流行病学,临床特征和传播的了解有限.
研究的目的:
- 在2022年爆发期间系统地审查和综合有关流行病学,临床特征和mopox传播的当前知识.
- 为公共卫生和临床指导提供有关mopox疫情的综合理解.
主要方法:
- 进行了对45篇同行评审文章和灰色文献的系统审查.
- 研究方法遵循系统审查和元分析首选报告项目 (PRISMA) 声明和Cochrane协作标准.
主要成果:
- 在全球范围内,mpox病例增加了约100倍,99%的病例发生在非流行地区.
- 大多数病例 (99%) 是男性 (70-98%),通常具有同性恋/双性恋行为 (30-60%),年龄在30-40.
- 传播通过直接接触发生 (90-100%),生殖器/生殖器病变普遍存在,喉炎/直肠炎增加;IIb类占主导地位.
结论:
- 这一系统性审查提供了关于mopox的流行病学,临床表现和传播的综合知识.
- 这些发现强调了2022年mopox疫情的独特特征,为公共卫生响应和临床管理提供了信息.
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