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Updated: Jul 14, 2025

In Situ Detection of Autoreactive CD4 T Cells in Brain and Heart Using Major Histocompatibility Complex Class II Dextramers
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抗原驱动的T细胞-巨细胞相互作用调解了histidyl-tRNA合成酶诱导的神经炎的先天性和适应性免疫之间的接口

Daniel P Reay1, Tracy Tabib1, Ying Wang2

  • 1Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, United States.

Frontiers in immunology
|October 9, 2023
PubMed
概括

异形性炎症性肌肉病 (IIM) 涉及复杂的免疫细胞相互作用. 在这种自身免疫性疾病中,T细胞和巨细胞对于驱动肌肉炎症至关重要,需要特定的信号通路来激活.

关键词:
这种HRS (histidyl-tRNA合成酶)一个T细胞细胞.适应性免疫是一种适应性免疫.这是先天免疫力.巨细胞是一个巨细胞.肌肉性肌肉性炎症 肌肉性肌肉炎

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