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Updated: Jul 14, 2025

Generation of Lymph Node-fat Pad Chimeras for the Study of Lymph Node Stromal Cell Origin
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三级淋巴体结构形成的机制:炎症和抗原性之间的合作

Shrijan Khanal1, Andreas Wieland2, Andrew J Gunderson1

  • 1Division of Surgical Oncology, Comprehensive Cancer Center, The Ohio State University, Columbus, OH, United States.

Frontiers in immunology
|October 9, 2023
PubMed
概括

瘤中的三级淋巴体结构 (TLS) 增强了抗瘤免疫力,并预测了免疫治疗反应. 了解TLS形成对于开发新的癌症疗法至关重要,但目前的小鼠模型限制了研究.

关键词:
B 细胞细胞B 细胞细胞一个T细胞细胞.T细胞 - B细胞的协作适应性免疫是一种适应性免疫.三级淋巴体结构的第三级淋巴体结构瘤免疫和免疫治疗的免疫力.

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