头骨底部碰撞瘤:巨大的非功能性垂体腺瘤和嗅觉沟脑膜瘤
Mehmet V Aydin1, Kivanc Yangi1, Ezgi Toptas2
1Neurological Surgery, Prof. Dr. Cemil Taşcıoğlu City Hospital, Istanbul, TUR.
Cureus
|October 9, 2023
概括
本案例研究突出了一个罕见的碰撞瘤,涉及嗅觉沟脑膜瘤和垂体腺瘤. 早期识别这些骨底部瘤对于有效的手术规划和患者的结果至关重要.
科学领域:
- 神经瘤学神经瘤学
- 头骨底部手术 头骨底部手术
- 病理学 病理学 病理学
背景情况:
- 碰撞瘤是一种罕见的实体,包括两个截然不同的相邻的瘤.
- 垂体腺瘤和脑膜瘤是常见的骨底部瘤,但它们作为碰撞瘤的同时发生非常罕见.
- 这一案例呈现了一种独特的嗅觉沟脑膜瘤与非功能性垂体腺瘤共存的实例.
研究的目的:
- 报告一个罕见的头骨基碰撞瘤病例.
- 讨论这种复杂病例的诊断挑战和手术管理.
- 强调在对前头骨底部病变的差异诊断中考虑碰撞瘤的重要性.
主要方法:
- 评估了一名65岁的男性患者,他表现出头痛和视力丧失的症状.
- 增强对比的头骨MRI显示出一个大型的,异质增强的前头骨底部损伤.
- 进行了两阶段的手术切除:最初是通过头切除,然后是通过内镜进行内切除.
- 组织病理学分析证实了垂体腺瘤和脑膜瘤 (世卫组织I级).
主要成果:
- 这位患者出现了嗅觉沟脑膜瘤和非功能性垂体腺瘤.
- 手术干预涉及通过骨切除部分切除,随后通过内镜切除残留瘤.
- 手术后的管理包括视神经减压和放射性手术的转诊.
- 病理学证实了垂体腺瘤和脑膜上皮质类型脑膜瘤 (世卫组织I级).
结论:
- 碰撞瘤虽然很少见,但必须在复杂的头骨底部病变的术前评估中考虑,特别是当MRI显示相邻的异质增强质量时.
- 在手术期间发现瘤一致性发生意想不到的变化,应该引起对碰撞瘤的怀疑.
- 准确的诊断对于适当的手术规划至关重要,确定需要放射性手术等辅助疗法,并了解瘤复发模式.
相关概念视频
01:14Cranial Bones: Superior and Posterior View
2.3K
The superior view of the cranium shows the frontal and paired parietal bones.
The frontal bone is the single bone that forms the forehead. At its anterior midline, between the eyebrows, there is a slight depression called the glabella. The frontal bone also forms the supraorbital margin of the orbit. Near the middle of this margin is the supraorbital foramen, the opening that provides passage for a sensory nerve to the forehead. The frontal bone is thickened just above each supraorbital margin,...
The frontal bone is the single bone that forms the forehead. At its anterior midline, between the eyebrows, there is a slight depression called the glabella. The frontal bone also forms the supraorbital margin of the orbit. Near the middle of this margin is the supraorbital foramen, the opening that provides passage for a sensory nerve to the forehead. The frontal bone is thickened just above each supraorbital margin,...
2.3K
01:27Cranial Bones: Lateral View
2.3K
The lateral view of the cranium is dominated by temporal, sphenoid, and ethmoid bones.
The temporal bone forms the lower lateral side of the skull. The temporal bone is subdivided into several regions. The flattened upper portion is the squamous portion of the temporal bone. Below this area and projecting anteriorly is the zygomatic process of the temporal bone, which forms the posterior portion of the zygomatic arch. Posteriorly is the mastoid portion of the temporal bone. Projecting...
The temporal bone forms the lower lateral side of the skull. The temporal bone is subdivided into several regions. The flattened upper portion is the squamous portion of the temporal bone. Below this area and projecting anteriorly is the zygomatic process of the temporal bone, which forms the posterior portion of the zygomatic arch. Posteriorly is the mastoid portion of the temporal bone. Projecting...
2.3K
01:08Overview of the Skull
4.7K
The cranium (skull) is the skeletal structure of the head that supports the face and protects the brain. It is subdivided into the facial bones and the brain case, or cranial vault. The facial bones underlie the facial structures, form the nasal cavity, enclose the eyeballs, and support the teeth of the upper and lower jaws.
The cranial vault surrounds and protects the brain and houses the middle and inner ear structures. This cavity is bounded superiorly by the rounded top of the skull, which...
The cranial vault surrounds and protects the brain and houses the middle and inner ear structures. This cavity is bounded superiorly by the rounded top of the skull, which...
4.7K
01:03Olfactory Receptors: Location and Structure
9.3K
The process of olfaction, also known as the sense of smell, is a sophisticated chemical response system. The specialized sensory neurons that facilitate this process, known as olfactory receptor neurons, are situated in an upper segment of the nasal cavity, known as the olfactory epithelium. Olfactory sensory neurons are bipolar, with their dendrites extending from the epithelium's apex into the mucus that lines the nasal cavity. Airborne molecules, when inhaled, traverse the olfactory...
9.3K