甜,兰和白精油的组合:使用混合物设计方法来优化一种新的完整抗微生物配方
Samiah Hamad Al-Mijalli1, Mohamed Jeddi2, Naoufal El Hachlafi2
1Department of Biology, College of Sciences, Princess Nourah Bint Abdulrahman University, Riyadh 11671, Saudi Arabia.
Heliyon
|October 9, 2023
概括
结合甜,兰和白精油 (EO),可以显示出协同作用的抗菌作用. 优化配方作为天然食品防腐剂,对抗常见的食源性病原体.
科学领域:
- 食品科学 食品科学 食品科学
- 微生物学 微生物学
- 植物化学 植物化学
背景情况:
- 药用植物,如甜,,和白拥有具有抗菌性能的挥发性油.
- 这些精油 (EO) 已知用于用途,并显示出对食品恶化的微生物的潜力.
研究的目的:
- 为了确定甜,和白EO的最佳抗菌配方.
- 通过混合物设计,研究EO组合的协同抗微生物作用.
主要方法:
- 精油通过水蒸提取,并通过气体染色学质谱法 (GC-MS) 分析.
- 使用微稀释方法评估的抗菌活性.
- 用于配方优化而使用的简单中心混合物设计.
主要成果:
- 在GC-MS中发现了一些关键化合物:甜和中的d-limonene,树中的citronellal.
- 这三种EO都表现出广泛的抗菌活性,白和甜的疗效更高.
- 在联合EO配方中观察到对*C. albicans*,*S. aureus*,*E. coli*,*S. enterica*和*B. cereus*等测试的微生物的协同效应.
结论:
- 优化组合的甜,,和白EOO表现出显著的协同作用的抗菌活性.
- 这些EO混合物显示出作为天然食品防腐剂和抗菌剂的潜力.
- 建议进行进一步的研究,以阐明作用机制和体内疗效.
相关概念视频
Antimicrobial Effectiveness
26
The effectiveness of antimicrobial agents depends on various factors influencing their ability to eliminate microbial populations. Larger microbial populations require more time for complete eradication, emphasizing the importance of population size analysis when evaluating antimicrobial efficacy.Microbial resistance to antimicrobial agents varies significantly. Highly resilient microorganisms include endospores, gram-negative bacteria, and non-enveloped viruses, while prions are exceptionally...
26
Chemical Agents for Microbial Control
40
Chemicals play important roles in controlling microbial growth by targeting microbial structures and functions as sanitizers, antiseptics, disinfectants, and sterilants.Alcohols are commonly used sanitizers, effectively disrupting lipid membranes, which compromises cell integrity. They are also used as antiseptics and disinfectants due to their rapid action and versatility.Phenols and their derivatives phenolics , known for denaturing proteins and disrupting cell membranes, are particularly...
40
Combined Effects of Drugs: Synergism
4.0K
Synergism is a useful mechanism where combining two or more drugs is more effective than each constituent used alone. Such combinations are also called supra-additive interactions. The drugs collectively enhance the final therapeutic effect by acting on different targets. Another advantage is that the low dose of each constituent drug is sufficient to achieve the desired effect. This helps reduce the duration of therapy and lower the adverse effects of these drugs.
Such synergistic combinations...
Such synergistic combinations...
4.0K
Surface Membrane Barriers
1.1K
The skin and mucous membranes serve as the primary line of defense against pathogens by providing both physical and chemical protection. These barriers are essential in preventing the entry and establishment of microbes, thereby maintaining the integrity of the host.
The outer layer of the skin, the epidermis, is a robust barrier comprising layers of closely packed keratinized cells. This dense arrangement prevents microbes from penetrating the body. The periodic shedding of epidermal cells...
The outer layer of the skin, the epidermis, is a robust barrier comprising layers of closely packed keratinized cells. This dense arrangement prevents microbes from penetrating the body. The periodic shedding of epidermal cells...
1.1K
Biological Methods for Microbial Control
45
Biological agents offer an effective means of controlling microbial growth by leveraging natural processes like predation, competition, and the secretion of antimicrobial substances.Predatory bacteria such as Bdellovibrio species target and kill pathogens like Salmonella and E. coli. They are widely used in poultry farms to control infections. Myxococcus species help combat plant-pathogenic fungi. These naturally occurring predators serve as eco-friendly alternatives to chemical pesticides and...
45
Antibiotic Selection
54.6K
Overview
54.6K


