不同冠状动脉复血管化手术对认知的影响:系统性审查
Wadha Tareq Althukair1, Shibili Nuhmani1
1Department of Physical Therapy, College of Applied Medical Sciences, Imam Abdulrahman Bin Faisal University, Dammam, Kingdom of Saudi Arabia.
Heliyon
|October 9, 2023
概括
不同的冠状动脉再血管化干预显示出各种认知效应,但将它们联系在一起的证据很弱. 需要进行更长的随访时间的进一步研究,以澄清这些程序后的长期认知衰退.
科学领域:
- 心脏病学 心脏病学
- 神经学 神经学
- 医疗干预 医疗干预
背景情况:
- 冠状动脉复血管化干预与手术后的认知衰退有关.
- 了解不同重血管化方法的长期认知影响至关重要.
研究的目的:
- 系统地审查和比较各种冠状动脉再血管化干预的长期认知效应.
- 识别与不同的手术和干预技术相关的认知结果的差异.
主要方法:
- 临床试验和队列研究的系统审查 (2009年1月至2023年1月) 来自Cochrane图书馆和MEDLINE.
- 包括的研究比较了至少两个干预措施,至少有三个月的随访时间.
- 偏差风险评估使用RoB 2用于RCT和ROBINS-1用于非随机研究.
主要成果:
- 包括五项研究 (3项RCT,2个队列) 和四项比较.
- 评估的干预措施:在上与下CABG,PCI,常规与微型心肺绕道,以及Endo-CABG.
- 虽然不同的干预措施显示出不同的认知效应,但没有确立确实的相关性.
结论:
- 目前的证据表明,重血管化技术之间存在不同的认知影响,但缺乏可靠的相关数据.
- 未来的研究应该优先考虑具有标准化,更长的随访期的比较研究.
- 需要进一步的研究来将长期认知衰退的影响与混变量分离开来.
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