具有非特异性肺功能测试模式的受试者的临床表现
James Tasch1, Samer Abujaber1, Laith Hattar2
1Division of Pulmonary, Critical Care and Sleep Medicine, Steward St. Elizabeth's Medical Center, Boston, MA, United States.
Open respiratory archives
|October 9, 2023
概括
非特异性模式 (NSP),一种保留比率受损螺旋计 (PRISm),不仅仅是阻塞性的. 临床症状和支气管扩展剂反应可能表明NSP患者的阻塞.
科学领域:
- 肺部病理学 肺部病理学
- 呼吸系统医学 呼吸系统医学
- 螺旋测量是一种螺旋测量.
背景情况:
- 非特异性模式 (NSP) 是保留比率受损螺旋计 (PRISm) 的一个子组.
- 从历史上看,NSP一直被归类为阻塞性肺病.
- PRISm越来越多地与慢性阻塞性肺病 (COPD) 的发展有关.
研究的目的:
- 调查NSP患者的临床特征.
- 为了澄清NSP在肺功能测试中的临床意义.
- 确定NSP是否应该被专门归类为阻碍性.
主要方法:
- 对符合NSP标准的111名 (BD前) 和79名 (BD后) 患者的门诊病历的回顾性审查.
- 根据医生诊断,将相关诊断分为"阻塞性"或"非阻塞性"组.
- 与诊断分类相关的临床症状和支气管扩展剂 (BD) 反应的分析.
主要成果:
- 患有阻塞性诊断的NSP患者更频繁地出现咳,喘息和唾液产生.
- 在NSP患者中,积极的BD反应与阻塞性肺病诊断有关.
- 大约三分之一的NSP患者没有被临床医生诊断为阻塞性肺病.
结论:
- NSP不仅仅是一种阻塞性肺病模式.
- 临床症状 (咳,喘息,) 和积极的BD反应支持NSP的阻塞性诊断.
- 需要进一步了解NSP的临床意义.
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