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萨尔科佩尼亚是发作性肝的患者不良后果的重要决定因素
Li Liu1,2, Shaohua Liu1,2, Meng Hao3
1Department of Endocrinology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
PeerJ
|October 9, 2023
概括
肉类,或低肌肉质量,是一个独立的风险因素,导致肝炎 (PLA) 患者的预后不佳. 患有肉类症的患者面临更高的不良结果的可能性,突出其临床意义.
科学领域:
- 肝病学 肝病学是一种肝病学.
- 老年病的医生 老年病的医生
- 放射学 放射学是一门学科.
背景情况:
- 低肌肉质量 (sarcopenia) 与各种疾病的预后不佳有关.
- 在肝 (PLA) 中萨尔科佩尼亚的临床意义尚未得到充分确立.
- 这项研究调查了肌肉质量和PLA患者预后之间的关联.
研究的目的:
- 为了确定萨科佩尼亚是否与患有肝炎的患者的不良结果有关.
- 为了评估肌肉质量指标在PLA的预后值.
主要方法:
- 对154名成年PLA患者的回顾性分析.
- 用CT扫描测量的肌肉脂肪指标在L3脊椎水平.
- 使用多变量逻辑回归和ROC曲线分析,对sarcopenia和非sarcopenia组进行比较.
主要成果:
- 骨肌指数 (SMI) 独立预测了PLA患者的不良结果 (95% CI [0.649-0.954],P=0.015).
- ROC分析显示,SMI可以预测男性 (AUC=0.718) 和女性 (AUC=0.714) 种群的不良结果.
- 为预测不良结果,确定了SMI的性别特定切断值.
结论:
- 萨尔科佩尼亚是一种独立的风险因素,导致肝脏的预后不佳.
- 患有肉症的患者在PLA中面临不良结果的风险增加.
- 在PLA患者中,SMI是一个有价值的预后指标.
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