带血中脂溶性维生素度与婴儿出生体重之间的关联
Guicun Yang1,2, Nianrong Wang1,2, Hao Liu1,2
1Department of Pediatrics, Chongqing Health Center for Women and Children, Chongqing, China.
Frontiers in endocrinology
|October 9, 2023
概括
婴儿出生体重与带血维生素A和E水平有关. 在较小的婴儿中,维生素A的含量较低,维生素E的含量较高,这表明对生长和代谢健康的潜在风险.
科学领域:
- 围产期营养学 围产期营养学
- 孕产妇和胎儿的医学
- 营养生物化学 营养生物化学
背景情况:
- 脂溶性维生素 (A,D,E) 对新陈代谢至关重要,可能会影响婴儿出生体重.
- 关于出生体重和脂溶性维生素之间的联系的现有证据是不一致的.
- 这项研究调查了带血维生素A,D和E水平与婴儿出生体重之间的关系.
研究的目的:
- 确定婴儿出生体重与带血中维生素A,D和E度之间的关联.
- 探索维生素失调对胎儿生长和未来代谢健康的潜在影响.
主要方法:
- 根据妊娠年龄组,199对母婴对被分为小 (SGA),适当 (AGA) 和大 (LGA).
- 血清中维生素A,D和E的度用高性能液体染色学双重质谱法量化.
- 进行了统计分析以评估相关性,并根据各种母婴因素进行调整.
主要成果:
- 与AGA和LGA组相比,SGA组的维生素A水平明显较低.
- 维生素E度在SGA组明显高于AGA和LGA组.
- 维生素D水平在各组之间没有显著差异. 经过调整后的分析证实了带血中的维生素A与出生体重之间的正相关性,以及维生素E与出生体重之间的负相关性.
结论:
- 婴儿出生体重与带血维生素A和E水平有显著的相关性.
- 婴儿中维生素A和E的不平衡可能是胎儿不理想生长和随后代谢障碍的危险因素.
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