维生素D与功能性消化不良的关联:一个病例控制研究
Dhriti Sundar Das1, Gautom Kumar Saharia2, Manas Kumar Panigrahi3
1Departments ofGeneral Medicine.
Annals of medicine and surgery (2012)
|October 9, 2023
概括
这项研究发现,维生素D缺乏和功能性消化不良 (FD) 之间存在显著的关联. 低维生素D水平在FD患者中更为常见,这表明补充剂在FD管理中的潜在作用.
科学领域:
- 胃肠病学 胃肠病学
- 内分泌学 在内分泌学.
- 营养科学 营养科学
背景情况:
- 大脑-肠轴受维生素D的影响.
- 功能性消化不良 (FD) 可能与较低的维生素D水平有关.
研究的目的:
- 调查维生素D水平与功能性消化不良 (FD) 之间的关联.
主要方法:
- 一项涉及150名FD患者和150名对照者的病例控制研究.
- FD的诊断是基于ROME IV标准的.
- 测量了血清维生素D,感知压力评分 (PSS) 和唾液氨酶.
主要成果:
- 在FD患者中,维生素D低水平的发病率显著更高 (73.3%与60%相比).
- 维生素D缺乏与FD相关,几率比为1.833.
- 在对共变量进行调整后,维生素D水平仍然与FD有显著的关联.
结论:
- 维生素D缺乏和功能性消化不良之间存在显著的关联.
- 需要进一步研究用于FD管理的维生素D补充剂.
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