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Liying Jiang^1,2, Xinyi Lin¹, Fenghua Chen¹

¹School of Electrical and Information Engineering, Zhengzhou University of Light Industry, Zhengzhou, 450002 China.

Microsystems & nanoengineering

|October 9, 2023

概括

早期发现瘤至关重要. 电化学和光生物传感器为分析体液中的瘤生物标志物提供了灵敏,快速和便携式方法,有助于诊断和监测.

科学领域:

生物医学工程生物医学工程
在瘤学瘤学.
分析化学分析化学

背景情况:

瘤发病率和死亡率的上升需要改进的诊断和监测工具.
体液中的生物标志物,包括循环瘤细胞和外体细胞,对癌症管理具有重大潜力.
在现场监测细胞标记物如端粒酶和miRNA对于了解瘤发育至关重要.

研究的目的:

审查使用电化学和光生物传感器在体液中检测瘤生物标志物的最新进展.
总结现场光监测和活细胞中瘤标记物的分析现状.
讨论挑战,并为开发新瘤标志物检测方法提供参考.

主要方法:

专注于电化学生物传感器,以获得高灵敏度,快速检测和可携带的瘤标志物的分析.
探索光信号分析,用于敏感和实时检测生物标志物.
审查已建立的技术,如ELISA,免疫染和质谱法进行比较.

主要成果:

电化学和光生物传感器由于灵敏度,速度和便携性而具有很高的偏好.
循环瘤细胞,DNA和外体提供丰富的信息,用于预测,诊断和预后.
端粒酶和miRNA的现场监测提供了对瘤进展的实时洞察.

结论:

生物传感器技术正在推进体液中的瘤生物标志物检测.
需要进一步开发,以克服广泛临床应用的技术挑战.
这些方法为未来的瘤诊断和监测策略提供了有希望的参考.

关键词:

生物传感器是一种生物传感器.传感器传感器传感器

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