肝硬化对接受心脏手术的患者的影响
Fei Liu1, Zi-Wei Li1, Xu-Rui Liu1
1Department of Gastrointestinal Surgery, the First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Global heart
|October 9, 2023
概括
肝硬化 (LC) 在接受心脏手术的患者中显著增加了术后并发症和死亡的风险. 在这些程序之前,仔细评估患者和肝功能评估至关重要.
科学领域:
- 心脏病学 心脏病学
- 肝病学 肝病学是一种肝病学.
- 手术结果研究研究.
背景情况:
- 心脏外科手术是一种复杂的手术,有可能导致严重的术后并发症.
- 预先存在的肝病,如肝硬化 (LC) 对心脏手术结果的影响尚未完全阐明.
- 了解这些风险对于患者管理和手术决策至关重要.
研究的目的:
- 调查肝硬化 (LC) 与心脏手术后术后并发症发生率之间的关联.
- 评估LC对经过心脏手术的患者的长期结果 (包括死亡率) 的影响.
- 在心脏外科手术过程中,确定LC作为潜在的风险因素.
主要方法:
- 在PubMed,Embase和Cochrane图书馆数据库中进行了系统的文献搜索.
- 分析了包括7项研究的数据,包括1,535,129名患者.
- 用元分析计算各种并发症和结果的几率比率 (OR) 和置信区间 (CI).
主要成果:
- 肝硬化 (LC) 被确定为整体术后并发症 (OR = 1.48) 的重要危险因素.
- 患有LC的患者表现出更高的肺 (OR = 1.86),胃肠道 (OR = 2.03),脏 (OR = 2.20),神经 (OR = 1.14) 和传染病 (OR = 2.02) 的并发症率.
- 在心脏手术后,LC与住院死亡率 (OR = 2.53) 和整体死亡率 (OR = 3.31) 的增加有关.
结论:
- 肝硬化 (LC) 是心脏手术患者不良术后并发症和较差的长期结果的重要危险因素.
- 特定的并发症,包括肺部,胃肠道,脏,神经和传染病问题,在LC患者中更为普遍.
- 对于预定进行心脏手术的LC患者来说,对肝功能进行彻底的术前评估和全面的风险评估至关重要.
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