scatterBrains:一个人类头部模型和伴侣光极位置的开放数据库,用于实现现实的蒙特卡洛光子模拟
Melissa M Wu1,2, Roarke Horstmeyer1, Stefan A Carp2
1Duke University, Department of Biomedical Engineering, Durham, North Carolina, United States.
Journal of biomedical optics
|October 9, 2023
概括
本研究引入了一个开源数据库,用于近红外光谱和分散相关性光谱的蒙特卡洛模拟的现实头模型. 这个资源简化了为NIRS/DCS研究创建准确的光传输模拟.
科学领域:
- 生物医学光学 生物医学光学
- 医疗成像医学成像
- 计算机建模 计算建模
背景情况:
- 蒙特卡洛 (MC) 模拟对于近红外光谱学 (NIRS) 和分散相关性光谱学 (DCS) 至关重要,但依赖于可访问的,现实的组织模型.
- 目前的局限性包括多样化,复杂的头模型的稀缺性和光极放置所需的手工努力,阻碍了广泛采用和大规模模拟,如机器学习培训.
研究的目的:
- 为NIRS/DCS模拟创建一个解剖学和光学现实的头部模型的开源数据库.
- 开发一个用户友好的软件管道来准备这些模型用于基于网格的MC模拟.
- 为NIRS/DCS社区提高先进模拟工具的可访问性.
主要方法:
- 从分段T1加权MRI扫描生成了16个解剖学头部模型.
- 将模型转换为四面体网状体积,每个模型大约有800个头皮表面位置.
- 开发了定制源和探测器放置的管道,并为MC模拟设置提供了指导.
主要成果:
- 创建了一个免费可用的数据库,包含 16 个现实的头部模型,分布式的 optode 位置.
- 开发并共享一个相关的软件管道,用于基于网状的MC模拟准备.
- 所有资源都可以通过 Github 上的 scatterBrains 项目访问.
结论:
- 分享资源为NIRS/DCS社区使用现实的头部几何体进行MC模拟.
- 该倡议旨在民主化对基于MRI的头部模型和虚拟 optode 放置的访问.
- 欢迎对数据库的贡献,以促进社区驱动的发展.
更多相关视频
04:02Serial Two-Photon Tomography of the Whole Marmoset Brain for Neuroanatomical Analyses
Published on: January 17, 2025
478
08:32Neurovascular Network Explorer 2.0: A Simple Tool for Exploring and Sharing a Database of Optogenetically-evoked Vasomotion in Mouse Cortex In Vivo
Published on: May 4, 2018
6.4K
相关概念视频
Electron Microscope Tomography and Single-particle Reconstruction
2.4K
Transmission electron microscopy (TEM) can be used to determine the 3D structure of biological samples with the help of techniques such as electron microscope tomography and single-particle reconstruction. While single-particle reconstruction can examine macromolecules and macromolecular complexes in vitro conditions only, tomography permits the study of cell components or small cells in vivo.
Electron Tomography
Electron tomography can be performed either in TEM or STEM (scanning transmission...
Electron Tomography
Electron tomography can be performed either in TEM or STEM (scanning transmission...
2.4K
Positron Emission Tomography
4.2K
Positron emission tomography (PET) is a medical imaging technique involving radiopharmaceuticals — substances that emit short-lived radiation. Although the first PET scanner was introduced in 1961, it took 15 more years before radiopharmaceuticals were combined with the technique and revolutionized its potential.
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body...
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body...
4.2K
