静止和轻度活跃的炎症性肠病的体力活动:系统性审查和元分析
Banke Oketola1,2, Olayinka Akinrolie1, Sandra Webber3
1Applied Health Sciences Program, Faculty of Graduate Studies, University of Manitoba, Winnipeg, Canada.
身体活动 (PA) 可能有助于减少患有静止/轻度炎症性肠病 (IBD) 的人的焦虑. 然而,关于改善生活质量等其他益处的证据目前尚不确定.
科学领域:
- 胃肠病学和肝病学
- 运动医学和运动科学 运动医学和运动科学
- 精神病学和心理学 精神病学和心理学
背景情况:
- 身体活动 (PA) 假设通过增强免疫反应,肌肉骨功能和心理健康,有利于患有炎症性肠道疾病 (IBD) 的个人.
- 有证据表明,PA可以改善与健康相关的生活质量 (HRQoL),并缓解疲劳,关节疼痛,腹痛,压力,焦虑和抑郁等症状,这些症状在静止或轻度IBD患者中存在.
研究的目的:
- 系统地审查身体活动 (PA) 的有效性和安全性,作为改善健康相关生活质量 (HRQoL) 和管理患有静止或轻度炎症性肠病 (IBD) 的成年人症状的辅助疗法.
主要方法:
- 在8个数据库和试验注册表中进行了全面的文献搜索,用于2011年至2023年期间以英语出版的随机对照试验 (RCT) 和非RCT.
- 该审查包括患有静止或轻度IBD的成年参与者 (≥18岁),检查PA作为辅助管理策略.
- 数据使用随机效应模型进行合成,计算标准化平均差异 (SMD) 或平均差异 (MD) 以95%的置信区间 (CI).
主要成果:
- 包括七个RCT和一个非RCT. 身体活动 (PA) 在减少焦虑症状方面显示出显著的益处 (SMD -0.35,95%CI -0.65至-0.05) 没有异质性 (I2 0%).
- 没有发现体力活动 (PA) 对健康相关生活质量 (HRQoL) 的显著益处证据 (SMD 0.34,95%CI -0.08至0.77),在研究中发现了很高的异质性 (I2 57%).
- 没有足够的证据可以得出关于PA对疲劳,关节疼痛,腹痛,压力和抑郁症的影响的结论. 所有包括的研究都报告PA是安全的.
结论:
- 身体活动 (PA) 有效地减少了患有静止或轻度炎症性肠病 (IBD) 的人的焦虑.
- 在研究研究PA在这个人群中的方法学中观察到显著的异质性.
- 对于体力活动 (PA) 类型和强度的标准化定义对于未来在平静/轻度IBD的成年人中的研究至关重要.
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