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在早产婴儿中治疗支气管肺功能障碍的超氧化失调酶
Martina Albertella1, Rahul R Gentyala2, Themistoklis Paraskevas3
1Faculty of Medicine, Genoa, Italy.
The Cochrane database of systematic reviews
|October 9, 2023
概括
关于超氧化物失调酶 (SOD) 在预防或治疗早产婴儿支气管肺功能失调症 (BPD) 的疗效,证据非常不确定. 需要更多的研究来确定SOD.
科学领域:
- 新生儿医学 新生儿医学
- 生物化学 生物化学
- 儿科肺病学 儿科肺病学
背景情况:
- 自由氧基有助于早产婴儿的支气管肺功能障碍症 (BPD).
- 超氧化脱酶 (SOD) 是一种天然的酶,可以防止氧化剂损伤.
- 临床试验已经研究了补充SOD以预防BPD.
结论:
- 关于SOD对BPD和早产婴儿相关并发症的疗效的证据非常不确定.
- 没有最近对早产婴儿的SOD进行的试验或正在进行的研究,最后一次试验是在1997/1998年.
- 需要进行进一步的临床前和观察性研究,以指导未来对SOD用于BPD预防的RCT.
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