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Updated: Jul 14, 2025

Accelerated Type 1 Diabetes Induction in Mice by Adoptive Transfer of Diabetogenic CD4+ T Cells
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在1型糖尿病中,MHC II类抗原处理和呈现途径受到调节

Ambroise Gilles1, Lan Hu2, Francesca Virdis3

  • 1Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ.

Journal of immunology (Baltimore, Md. : 1950)
|October 9, 2023
PubMed
概括

1型糖尿病 (T1D) 破坏了MHCII类抗原处理途径,显示MHCII-CLIP水平的增加以及免疫细胞中的HLA-DM (DM) 和HLA-DO (DO) 表达的改变,这表明T1D患者的途径严重失调.

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