接受实体器官移植的儿童的骨健康
Bianca Pinto1, Radhika Muzumdar, Natalie Hecht Baldauff
1UPMC Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Current opinion in pediatrics
|October 9, 2023
概括
儿科移植接受者面临高风险的代谢性骨病,影响骨折风险在以后的生活. 早期监测和量身定制的治疗对于改善这些成长中的个体的骨健康至关重要.
科学领域:
- 儿科内分泌学 儿科内分泌学
- 移植医学 移植医学
- 代谢性骨疾病 代谢性骨疾病
背景情况:
- 儿童固体器官移植接受者容易患上移植前和移植后的代谢性骨病.
- 儿童骨折增加了成人骨折的风险,需要对移植患者进行警监测.
- 新兴研究表明,纤维细胞生长因子23与CKD-MBD和肝脏骨质疏松症有关.
结论:
- 在移植后优化矿物质平衡,营养和身体条件至关重要.
- 早期发现和治疗代谢性骨病可以改善儿童移植幸存者的长期骨健康.
- 解决代谢性骨病改善了儿科移植接受者的过渡到成年.
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