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对尼帕病毒表面蛋白质突变的生物信息研究:与以弗林B2受体的分子对接,分子动力学模拟和结构影响分析

Emre Aktaş1, İrem Saygılı1, Elif Kahveci1

  • 1Faculty of Art and Science, Molecular Biology and Genetics, Yıldız Technical University, Istanbul, Turkey.

Microbiology and immunology
|October 9, 2023
PubMed
概括

尼帕病毒在G和F蛋白中的突变,如G273S和Y228H,影响病毒的进入和稳定性. 了解这些变化对于开发有效的尼帕病毒疫苗和治疗方法至关重要.

关键词:
尼帕病毒突变的突变尼帕病毒的蛋白质.生物信息学分析分析疫苗研发疫苗的发展.

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Globular and Fibrous Proteins02:21

Globular and Fibrous Proteins

Many proteins can be classified into two distinct subtypes - globular or fibrous. These two types differ in their shapes and solubilities.
Globular proteins are also known as spheroproteins and typically are approximately round in shape. They contain a mix of amino acid types and contain differing sequences in their primary structures. Globular proteins have many different functions, such as enzymes, cellular messengers, and molecular transporters. These roles often require the proteins to be...