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食道癌:概述,危险因素和增加原因
Steve Lander1, Eric Lander2, Michael K Gibson2
1Department of Medicine, The University of Tennessee Health Sciences Center, Memphis, TN, USA. slandermd@gmail.com.
Current gastroenterology reports
|October 9, 2023
概括
食道癌亚型在全球范围内发生变化,原因是肥胖和西方饮食等风险因素的变化. 了解这些流行病学变化是减少食道癌症的全球负担的关键.
科学领域:
- 在瘤学瘤学.
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 食道癌 (EC) 呈现出全球显著的发病率和死亡率.
- 在全球范围内,EC亚型的流行病学趋势正在演变.
- 了解风险因素对于管理EC发病率和流行率至关重要.
研究的目的:
- 审查影响全球EC亚型发病率和流行率的关键风险因素.
- 分析食道癌亚型的流行病学变化.
- 要突出原因背后的不断变化的欧洲共同体景观.
主要方法:
- 关于食道癌风险因素的文献综述.
- 对EC亚型的全球流行病学数据的分析.
- 发病率的相关性与生活方式和饮食变化发生的变化.
主要成果:
- 从食道状细胞癌 (ESCC) 到食道腺癌 (AC) 的发生率发生了全球变化.
- 西方国家肥胖率的增加与AC发病率的上升有关.
- 在亚洲采用西方饮食与增加AC患病率有关.
- 病理生理学,风险因素和表现在ESCC和AC之间有所不同.
结论:
- 改变的生活方式和风险因素显著改变了欧洲共同体的流行病学.
- 公共卫生倡议和识字计划可以帮助减轻EC的全球负担.
- 对风险因素的进一步分析对于有针对性的干预措施至关重要.
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