改善艾滋病毒暴露前预防 (PrEP) 坚持和留在护理中的情况:从国家实施的PrEP计划中进行流程评估和建议开发
Jennifer MacDonald1, Claudia S Estcourt1,2, Paul Flowers3
1Research Centre for Health (ReaCH), Glasgow Caledonian University, Glasgow, Scotland, United Kingdom.
PloS one
|October 9, 2023
概括
坚持艾滋病毒暴露前预防 (PrEP) 对于预防艾滋病毒传播至关重要. 这项研究确定了PrEP使用和保留护理的障碍和促进因素,并提供基于证据的建议,以提高计划的有效性.
科学领域:
- 公共卫生 公共卫生
- 预防艾滋病毒 预防艾滋病毒
- 实施科学 实施科学
背景情况:
- 艾滋病毒暴露前预防 (PrEP) 是全球艾滋病毒传播消除策略的基石.
- 有效的PrEP实施需要持续的坚持和留在护理中,这带来了重大挑战.
- 苏格兰PrEP计划的评估旨在识别和解决这些挑战.
研究的目的:
- 在苏格兰的PrEP计划中探索PrEP遵守和保留护理的障碍和促进者.
- 系统地制定基于证据的,理论上知情的建议,以提高PrEP计划的有效性.
- 在公共卫生,临床和社区实践中确定协作干预点.
主要方法:
- 与PrEP使用者,医疗保健专业人员和非政府组织工作人员进行半结构化访谈和焦点小组.
- 专题分析以确定关键的障碍和促进者.
- 应用实施科学工具 (理论领域框架,干预功能,行为变化技术分类学,APEASE标准) 和专家意见,以产生建议.
主要成果:
- 主要障碍包括复杂的按需剂量,提前停止PrEP,副作用,不灵活的预约和耻辱.
- 确定的促进者包括灵活的日程安排,预约提醒和非出席者的后续流程.
- 产生了25条建议,重点是个性化护理,系统提醒,合作伙伴支持,明确的剂量指导和副作用管理.
结论:
- 在PrEP的遵守和保留方面的挑战可以降低其在个人和人口层面上的有效性.
- 合作干预对于解决已识别的障碍和提高PrEP计划结果至关重要.
- 该研究提供了可行的解决方案,以改善PrEP的交付和吸收.
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