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Updated: Jul 14, 2025

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在德拉维特综合征模型中,反感性寡核酸恢复了兴奋性,GABA信号和电流密度

Yukun Yuan1, Luis Lopez-Santiago1, Nicholas Denomme1

  • 1Department of Pharmacology, University of Michigan, Ann Arbor, MI 48109, USA.

Brain : a journal of neurology
|October 9, 2023
PubMed
概括

反感性寡核酸ASO-84通过恢复Nav1.1表达来纠正德拉维特综合征小鼠的内部神经元功能障碍. 这种方法对治疗这种严重的神经障碍有希望.

关键词:
这是一种反意义的寡核酸.是一种.通道中的.治疗药物 治疗药物

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