在体外消化条件下喷射植物及其受控释放特性
Handan Başünal Gülmez1, Ayhan Topuz1
1Akdeniz University, Faculty of Engineering, Department of Food Engineering, 07058 Antalya, Turkiye.
Food chemistry
|October 9, 2023
概括
电子喷雾封装的植物来提高生物可用性. 优化载体增强了肠道条件的释放,克服了传统植物醇使用的局限性.
科学领域:
- 食品科学与技术 食品科学与技术
- 营养生物化学 营养生物化学
- 材料科学 材料科学 材料科学
背景情况:
- 植物醇有效降低人类的胆固醇和LDL度.
- 植物醇使用的挑战包括溶解性差,高点,状的味道,容易氧化,降低吸收和生物可用性.
- 封装提供了一个解决方案,以提高植物的稳定性和输送.
研究的目的:
- 用电喷涂来封装植物醇混合物以克服限制.
- 优化载体材料和度,以控制植物的释放,最大限度地减少在胃中的释放,最大限度地增加在肠道中的释放.
- 在模拟的胃和肠道条件下评估封装植物的释放特征.
主要方法:
- 电喷技术用于植物囊封装.
- 使用混合物设计方法来优化载体材料组成 (乳清蛋白分离物,胰岛素,耐性粉).
- 在体外释放研究中,使用胃和肠道溶液模型进行了实验.
主要成果:
- 最优的载体成分被确定为7.19克乳清蛋白分离物/100毫升,9.03克胰岛素/100毫升和3.78克耐性粉/100毫升.
- 电子喷射的植物囊表现出受控释放,在模拟的胃条件下释放了115.19 mg/kg.
- 在模拟的肠道条件下,观察到312.49mg/kg的显著更高的释放量.
结论:
- 电子喷雾成功生产了具有增强稳定性和受控释放性能的植物微囊.
- 优化的配方显著改善了植物在肠道环境中的释放,解决了生物可用性问题.
- 这种封装策略有望提高功能性食品中植物的有效性和应用.
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