连续与间歇性催产素诱导劳动在无产妇患者:一个随机对照试验
Gal Bachar1, Hiba Abu-Rass1, Naama Farago1
1Department of Obstetrics and Gynecology, Rambam Health Care Campus, Haifa, Israel (Drs Gal, Hiba, Naama, Naphtali, Gili, Yoav, Chen, Mr Nirit, Drs Nizar, Yuval, Yaniv, Zeev, and Dana).
American journal of obstetrics & gynecology MFM
|October 9, 2023
概括
持续的催产素输液用于诱导劳动的无产妇患者具有有利的子宫导致更快的分娩时间和改善母亲的满意度. 这种方法还可以降低胆肌炎的发病率,而不会增加不良结果.
科学领域:
- 产科和妇科 产科和妇科
- 生殖医学 生殖医学
- 临床试验 临床试验
背景情况:
- 催产素是诱导分娩的主要药物,但最佳输液方案需要进一步调查.
- 确定施用催产素的理想持续时间和方法对于改善分娩结果至关重要.
研究的目的:
- 为了比较连续与间歇性催产素输液的疗效,用于分娩诱导.
- 评估催产素输液持续时间对24小时分娩率,分娩时间和患者体验的影响.
主要方法:
- 这是一项随机对照试验,涉及153名无胎儿患者,Bishop分数≥6.6.
- 患者在分娩前接受连续 (16小时) 或间歇 (8小时) 的催产素输液.
- 主要结局是24小时内分娩;次要结局包括时间到分娩,分娩方式和孕产妇/新生儿结局.
主要成果:
- 持续的催产素输液导致在24小时内分娩的比率更高 (79.73%与62.96%相比),分娩时间更短 (9.3±3.7小时与21±11.7小时相比).
- 连续组出现的胆肌炎较少 (9.46%对21%) 和更高的母亲满意度.
- 剖腹产产率和不良母亲/新生儿结果在各组之间是相似的.
结论:
- 持续的催产素输液似乎优于间歇性输液,用于在没有产妇的妇女中诱导分娩,并具有良好的子宫.
- 这种方法加快了分娩速度,降低了感染风险,并提高了患者的满意度,而不会影响安全.
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