早期的营养和成年后的生活结果
João Guilherme Bezerra Alves1, Lucas Victor Alves2
1Department of Pediatrics, Instituto de Medicina Integral Prof. Fernando Figueira (IMIP), Recife, PE, Brazil.
早期营养显著影响成人健康,通过表观遗传变化影响慢性疾病. 专注于生命的前1000天对于公共卫生至关重要,以预防终身疾病.
科学领域:
- 营养科学 营养科学
- 发育生物学是发展生物学.
- 公共卫生 公共卫生
背景情况:
- 健康和疾病的发育起源 (DOHaD) 假设将早期生活条件与成人健康结果联系起来.
- 早期营养是影响晚年慢性疾病发展的关键因素.
研究的目的:
- 审查有关早期营养与慢性成人疾病的证据.
- 突出营养对成人身高,肥胖,代谢综合征,2型糖尿病,心血管疾病和生殖健康的影响.
主要方法:
- 对研究早期营养和DOHaD的文献综述.
- 搜索的数据库包括Medline,Embase,Cochrane数据库和Lilacs. 这些数据库的搜索数据库包括Medline,Embase,Cochrane数据库和Lilacs.
主要成果:
- 早期的营养缺乏或过量可以导致长期后果的表观遗传修饰.
- 强有力的证据支持早期营养在各种成人慢性疾病的起源中的作用.
结论:
- 早期营养引起的表观遗传变化有助于慢性疾病的发展.
- 公共卫生干预措施应优先考虑生命的前1000天 (怀孕到两岁) 的营养,以减轻成人慢性疾病.
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