在接受脏替代疗法的患者中,COVID-19的发生率和结果
Siribha Changsirikulchai1, Pornpen Sangthawan2, Jirayut Janma1
1Division of Nephrology, Department of Medicine, Faculty of Medicine, Srinakharinwirot University, Nakhonnayok, Thailand.
Kidney research and clinical practice
|October 9, 2023
概括
血液透析 (HD) 患者的COVID-19感染率较高. 疫苗接种显著降低了脏患者的死亡率,这强调了需要更广泛地接种疫苗的必要性.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 在接受血液透析 (HD),腹腔透析 (PD) 和移植 (KT) 的病患者中研究了COVID-19的结果.
- 专注于由国家卫生安全办公室 (NHSO) 偿还的患者.
研究的目的:
- 确定COVID-19在HD,PD和KT患者中的发病率和死亡率.
- 为了确定与COVID-19结果相关的因素,包括疫苗接种状态和并发症.
主要方法:
- 电子索赔数据库的回顾性队列分析 (2020年1月 - 2021年12月).
- 评估了85,305名患者的COVID-19感染,疫苗接种状态,并发病,死亡和治疗费用.
- 评估了患者特征,疫苗接种和死亡率之间的关联.
主要成果:
- COVID-19感染的发病率为HD患者的4.9%,PD患者的3.4%,KT患者的3.3%.
- 疫苗接种率在KT (76.93%) 中最高,其次是HD (70.65%) 和PD (51.34%).
- 与PD (18.41%) 和HD (21.40%) 相比,KT的死亡率较低 (8.42%). 接种疫苗显著降低了死亡率 (或0.3两剂).
结论:
- 与PD和KT患者相比,血液透析患者的COVID-19感染发病率较高.
- 接种COVID-19疫苗对于减少病患者的死亡率至关重要.
- 鼓励疫苗接种与国家卫生政策一致,以保护弱势群体.
相关概念视频
Kidney Transplant III: Nursing Management
23
Postoperative Nursing Management for Kidney Transplant PatientsPostoperative nursing management care includes monitoring the surgical site, encouraging early movement, and promoting lung health through breathing exercises. Nurses also administer prescribed medications like H2-blockers, such as famotidine, or proton pump inhibitors, like omeprazole, to help prevent gastrointestinal ulcers and bleeding. Fungal infections in the mouth and bladder can result from immunosuppressive and antibiotic...
23
Kidney Transplant I: Introduction
14
A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
14
Acute Kidney Injury III: Clinical Manifestations
15
Acute Kidney Injury (AKI) progresses through distinct clinical phases: the oliguric, diuretic, and recovery phases, each marked by unique manifestations and challenges.Oliguric Phase:The oliguric phase is the initial stage of AKI, typically lasting 10 to 14 days. This phase is marked by a significant reduction in urine output, usually less than 400 mL per day, indicating decreased kidney function. Fluid retention is a prominent feature, leading to symptoms such as edema, hypertension, and...
15
Continuous Renal Replacement Therapy
38
Continuous Renal Replacement Therapy, also known as CRRT, is a procedural treatment for acute kidney injury (AKI) that gradually removes uremic toxins and fluids while maintaining acid-base balance and stabilizing electrolytes. It is particularly useful for hemodynamically unstable patients. Unlike intermittent hemodialysis, which is faster, CRRT provides a gentler approach over 24 hours, closely mimicking the function of natural kidneys. However, CRRT is not ideal for patients with...
38
Acute Kidney Injury I: Introduction
15
Introduction:Acute Kidney Injury (AKI) describes a swift decrease in kidney function occurring over hours to days, characterized by the kidneys' failure to remove waste products from the bloodstream. This leads to dangerous complications like metabolic acidosis, fluid overload, and electrolyte imbalances, such as hyperkalemia, which can cause life-threatening arrhythmias. AKI is common in both hospital and outpatient settings, often triggered by dehydration, sepsis, or exposure to nephrotoxic...
15
Kidney Transplant II: Surgical Procedure
22
Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living...
22


