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Updated: Aug 3, 2026

Establishment of a Human Multiple Myeloma Xenograft Model in the Chicken to Study Tumor Growth, Invasion and Angiogenesis
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Published on: May 1, 2015

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基于基因组信息的多发性骨髓瘤可用药基因的鉴定

Rahmat Dani Satria1,2, Lalu Muhammad Irham3,4, Wirawan Adikusuma5,6

  • 1Department of Clinical Pathology and Laboratory Medicine, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada, Yogyakarta 55281, Indonesia.

Genomics & informatics
|October 9, 2023
PubMed
概括

这项研究确定了14种新的多发性骨髓瘤 (MM) 遗传风险因素. 它还揭示了10种潜在的药物,包括重定向药物,用于MM治疗,推进基因组驱动药物发现.

关键词:
生物风险基因 生物风险基因药物重新定位 药物重新定位基因组变异的基因组变异多发性骨髓瘤是多发性骨髓瘤的一种.

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Pharmacogenomics: Identification of New Drug Targets

Advances in genomics have profoundly influenced drug discovery by increasing both the speed and accuracy of pharmaceutical development. Pharmacogenomics, which examines how genetic variation influences drug response, facilitates the identification of novel therapeutic targets and enables patient stratification for personalized treatment. These strategies contribute to improved drug efficacy, minimized adverse effects, and more efficient clinical trial design.Mapping genetic differences...