卷积磁共振成像:复杂发烧发作和复发的简单发烧发作之间的区别
Berrin Cavusoglu1, Çigdem Ozer Gokaslan2, Dilek Cavusoglu3
1Department of Medical Physics, Institute of Health Sciences, Dokuz Eylül University, Izmir, Turkey.
Brain & development
|October 9, 2023
概括
与简单的FS相比,患有复杂发烧 (FS) 的儿童表现出明显的脑结构差异. 具体来说,膜和核的变化可能表明与复杂发烧有关的微观结构变化.
科学领域:
- 神经成像是一种神经成像.
- 儿科神经学 儿科神经学
- 大脑形态学 大脑形态学
背景情况:
- 发烧性发作 (FS) 在儿童时期很常见.
- 区分复杂的和简单的FS对于预后至关重要.
- 了解复杂FS的神经解剖学的基础是很重要的.
研究的目的:
- 调查复杂FS和复发简单FS的儿童之间的皮质和皮质下大脑结构的体积差异.
- 识别与复杂的FS相关的特定大脑形态模式.
- 探索FS诱导变化的潜在神经成像标记.
主要方法:
- 结构磁共振成像 (MRI) 用于25名复杂FS患者和25名复发简单FS患者.
- 基于voxel的形态测量 (CAT12/SPM12) 分析了皮质体积.
- FSL-FIRST量化了皮层下深灰色物质体积和不对称性指数.
主要成果:
- 与简单的FS相比,复杂FS患者的左门和右核体积减少.
- 患有复杂FS的患者在核中显示出明显更高的不对称指数.
- 这些发现突出了复杂的FS中特定的皮质下结构变化.
结论:
- 大脑结构的体积测量分析可以作为FS诱导的微观结构变化的标记.
- 这项研究是首次报告发烧性发作中膜和内核的变化.
- 神经成像可能有助于了解复杂发烧的病理生理学.
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