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Updated: Jul 14, 2025

Optimized LC-MS/MS Method for the High-throughput Analysis of Clinical Samples of Ivacaftor, Its Major Metabolites, and Lumacaftor in Biological Fluids of Cystic Fibrosis Patients
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Optimized LC-MS/MS Method for the High-throughput Analysis of Clinical Samples of Ivacaftor, Its Major Metabolites, and Lumacaftor in Biological Fluids of Cystic Fibrosis Patients

Published on: October 15, 2017

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用 ivacaftor 治疗后便脂质组的变化,而没有微生物组或胆酸的变化

Rosara Bass1, Ceylan Tanes2, Kyle Bittinger2

  • 1Department of Pediatrics, Division of Gastroenterology, Hepatology and Nutrition, Children's Hospital of Philadelphia, 3401 Civic Center Blvd, Philadelphia, PA, 19104, USA; Perelman School of Medicine, University of Pennsylvania, 3400 Civic Center Blvd, Philadelphia, PA, 19104, USA.

Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society
|October 9, 2023
PubMed
概括

伊瓦卡夫托尔治疗没有改变囊性纤维化 (CF) 患者的肠道微生物群. 然而,它确实导致了便脂质概况的变化,特别是在胰腺不足和足够的CF组之间减弱了差异.

关键词:
胆汁酸 胆汁酸是一种囊性纤维化症是什么肠道 肠道 肠道这就是Ivacaftor的原因.脂质组 (lipidome) 是一种脂质组 (lipidome) 的组成部分.微生物组是一个微生物组.子 子 子 子

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