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Updated: Jul 14, 2025

Silencing of BRCA2 to Identify Novel BRCA2-regulated Biological Functions in Cultured Human Cells
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Silencing of BRCA2 to Identify Novel BRCA2-regulated Biological Functions in Cultured Human Cells

Published on: August 12, 2015

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一个BRCA2生殖系突变和高表达的免疫检查点在TNBC患者

Yuyi Han1,2, Valentina Rovella1, Artem Smirnov1,3

  • 1Department of Experimental Medicine, TOR, University of Rome Tor Vergata, 00133, Rome, Italy.

Cell death discovery
|October 9, 2023
PubMed
概括

这项案例研究揭示了BRCA2基因突变,同源重组缺陷和三阴性乳腺癌 (TNBC) 免疫检查点表达增加之间的联系. 在TNBC患者的基因查可以预测免疫疗法反应.

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