预测高血压的老年人轻度认知障碍的诺莫图
Lu Jingyu1, Ding Wen2, Zhang Liping3
1Nursing Department, General Hospital of Ningxia Medical University, 804 Shengli Street, Xingqing District, Yinchuan, China.
BMC neurology
|October 9, 2023
概括
这项研究开发了一种名谱,用于预测高血压的老年人轻度认知障碍 (MCI). 该工具有助于早期识别高风险个体,可能降低痴呆风险.
科学领域:
- 老年学是指老年学的学科.
- 神经学 神经学
- 心脏病学 心脏病学
背景情况:
- 高血压和低血压与认知功能障碍有关.
- 在高血压患者中早期发现轻度认知障碍 (MCI) 对预防痴呆症至关重要.
- 现有的MCI风险预测模型对于年长的高血压成年人来说是不够的.
研究的目的:
- 开发和验证一种名谱模型,用于预测高血压老年患者的MCI.
- 为早期风险评估和干预提供一个工具.
主要方法:
- 使用345名老年高血压患者 (建模组) 的数据开发了一个名图.
- 后勤回归确定了MCI的风险因素.
- 在内部和外部使用146名患者验证了nomogram的有效性和歧视性.
主要成果:
- 确定了MCI的11个风险因素,包括高血压等级,教育,糖尿病,高血压持续时间,压力,吸烟,运动,阅读,社会支持,睡眠障碍和药物遵守.
- 命名图显示了良好的匹配 (P=0.98建模,P=0.96验证) 和歧视 (AUC=0.795建模,AUC=0.765验证).
结论:
- 经过验证的血压表可以有效地识别老年高血压患者中患有MCI的高风险个体.
- 该工具支持社区医务人员在早期MCI风险评估和管理.
- 早期干预可能会减少痴呆症的进展.
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