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Updated: Jul 14, 2025

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在抗化学性白血病细胞中,CADM1损害了miR-1246对促进细胞循环进展的作用

Bei Xie1, Lei Zhao2, Zhewen Zhang3

  • 1Department of Immunology, School of Basic Medical Sciences, Lanzhou University, No. 199 Donggang West Road, Lanzhou, 730000, Gansu, China. xieb@lzu.edu.cn.

BMC cancer
|October 9, 2023
PubMed
概括

微RNA-1246 (miR-1246) 通过抑制调节细胞循环进展的CADM1来促进白血病药物耐药性. 抑制miR-1246或恢复CADM1可以提高白血病的化疗敏感性.

关键词:
在CADM1中.在CDKs/Cyclins轴上细胞循环的细胞周期化疗耐药白血病细胞在 miR-1246 的位置上.

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