在突破COVID感染后,在南印度队列中长期COVID的特征和预测风险评分;一个潜在的单中心研究研究
Pranav Nair1, Chithira V Nair2, Kiran G Kulirankal2
1Department of Radiation Oncology, Amrita Institute of Medical Science and Research Centre, Amrita Vishwa Vidyapeetham, Kochi, Kerala, India.
BMC infectious diseases
|October 9, 2023
概括
长期COVID影响近40%的人在突破性感染后,随着年龄的增长和诸如高血压等并发症增加风险. 预测得分可以帮助识别那些需要对长期COVID进行更密切监测的人.
科学领域:
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 随着COVID-19大流行的结束,人们的注意力转移到了长期的并发症上,比如长期COVID.
- 长期COVID涉及最初感染后持续的症状.
- 这项研究检查了南印度人中长期COVID的突破性ChAdOx1 n-Cov-2疫苗感染.
研究的目的:
- 描述长期COVID的发生率.
- 概述临床特征和风险概况.
- 在接种疫苗的南印度队列中评估长期COVID突破后感染.
主要方法:
- 一个单一中心,基于医院的前性观察性研究 (2021年10月至12月).
- 成年患者 (18岁以上) 确诊COVID-19并至少包括一个疫苗剂量.
- 通过调查问卷收集的数据在阴性测试后的2,6和12周;用于风险评估的倾向性得分.
主要成果:
- 414名患者中有164名 (39.6%) 报告了超过6周的长期COVID症状.
- 在65岁以上的患者和伴随疾病 (糖尿病,高血压,喘) 患者中发生率更高.
- 年龄,高血压和喘被确定为重要的预测因素;与并发症相关的症状负担.
结论:
- 长期COVID在12周时普遍存在,即使在非住院患者中,也需要康复后的随访.
- 提出的预测风险评分可以帮助识别有风险的个人.
- 需要进一步研究长期COVID对生活质量的影响和康复策略.
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