在外科手术后长期暴露于环境颗粒物和臭氧污染,导致下肢深静脉血栓形成:中国北京的一项回顾性病例对照研究
Qin Xiong1, Wanzhou Wang2,3,4, Yong Wang5
1Education Department, Beijing Shijitan Hospital, Capital Medical University, Beijing, 100038, China. xiongqinsmile@163.com.
BMC public health
|October 9, 2023
概括
暴露于PM2.5,PM10和臭氧等空气污染物增加了手术后下肢深静脉血栓症 (LEDVT) 的风险. 这项研究强调了空气质量和术后并发症之间的联系.
科学领域:
- 环境健康 环境健康
- 肺部医学 肺部医学
- 血管外科 血管外科
背景情况:
- 下肢深静脉血栓形成 (LEDVT) 是一个频繁且可能致命的术后并发症.
- 关于环境空气污染与LEDVT之间的联系的证据有限,尤其是在发展中国家.
研究的目的:
- 调查暴露于细颗粒物 (PM2.5),可吸入颗粒物 (PM10) 和臭氧 (O3) 与手术患者患LEDVT的几率之间的关系.
- 提供来自发展中国家 (北京,中国) 的证据,说明这一环境健康问题.
主要方法:
- 一项追溯病例控制研究,涉及302例LEDVT病例和302例来自北京一家普通医院的对照.
- 分析的重点是指数日期前3个月,6个月和2年的PM2.5,PM10和O3平均暴露水平.
主要成果:
- 增加LEDVT的几率与不同平均期的PM2.5,PM10和O3度较高有关.
- 例如,两年平均PM2.5增加10μg/m3与LEDVT的1.30赔率比率 (OR) 有关.
- 长期暴露在臭氧中显示出特别强烈的关联,LEDVT的OR为2.08,每10μg/m3增加2年的平均值.
结论:
- 长期暴露于环境PM2.5,PM10和O3可能会增加手术后患者LEDVT的风险.
- 这些发现表明,空气污染可能是导致手术患者不良临床结果的因素,并可能为预防策略提供信息.
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