患有慢性病的患者的便秘
Ra Ri Cha1, Seon-Young Park2, Michael Camilleri3
1Department of Internal Medicine, Gyeongsang National University Changwon Hospital, Gyeongsang National University College of Medicine, Changwon, Gyeongsangnam-do, Korea.
Journal of neurogastroenterology and motility
|October 10, 2023
概括
便秘在慢性病 (CKD) 中很常见,并可能使功能恶化. 乳糖, lubiprostone, linaclotide, plecanatide, tenapanor 和调整剂量的 prucalopride 等特定的治疗方法为患有便秘的CKD患者提供了好处.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 胃肠病学 胃肠病学
- 药理学 药理学是指药理学的学科.
背景情况:
- 便秘是慢性脏病 (CKD) 患者的一个普遍问题.
- 它与不良健康结果有关,包括加速功能下降.
- 原因包括药物,饮食和慢性病患者的肠道功能变化.
研究的目的:
- 审查CKD患者便秘的机制.
- 概述CKD中便秘的当前和新兴管理策略.
- 为了提供医生的观点来治疗这个人群中的便秘.
主要方法:
- 关于慢性病中便秘研究的文献综述.
- 分析各种药理学药物的疗效和安全性.
- 评估非药物干预及其影响.
主要成果:
- 标准药可能是无效或不安全的;一些药物显示有前途.
- 乳糖, lubiprostone, linaclotide, plecanatide 和 tenapanor 证明了潜在的益处和安全性.
- 普鲁卡洛普里德可能是有效的,但需要对CKD患者进行剂量调整.
结论:
- 便秘显著影响CKD患者的健康和脏预后.
- 几种新型药物为治疗慢性脏疾病中便秘提供了更好的疗效和安全性.
- 个性化治疗策略对于优化CKD患者便秘的治疗结果至关重要.
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