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长时间的气管输管在ICU是肝移植手术后关节脱位的可能危险因素:一项回顾性病例对照研究
Wenqing Yan1,2, Weihua Dong1,2, Zhi Chen3
1Department of Emergency, Jiangxi Provincial People's Hospital, Nanchang, Jiangxi, China (mainland).
Annals of transplantation
|October 10, 2023
概括
在3.57%的肝移植患者中,发生了关节突变 (AD). 在重症监护室 (ICU) 进行长时间的气管输管被确定为这种罕见的麻醉并发症的重要危险因素.
科学领域:
- 麻醉学 麻醉学
- 移植手术 移植手术
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
背景情况:
- 耳突变 (AD) 是全身麻醉和气管管道输液后的一种罕见并发症,报告的发病率为0.009%至0.097%.
- 识别AD的风险因素至关重要,特别是在复杂的外科手术中,如肝移植.
研究的目的:
- 在接受肝移植的患者中,以确定关节突变 (AD) 的发生率.
- 在这个患者群体中确定与AD相关的特定风险因素.
主要方法:
- 追溯病例控制研究,涉及476名肝移植患者 (2013年1月至2022年12月).
- 根据麻醉类型和麻醉师,17名患有AD的患者与68名匹配的对照 (4:1比) 进行了比较.
- 收集的数据包括患者特征,麻醉因素和手术因素;用于识别风险因素的后勤回归分析.
主要成果:
- 肝移植患者中AD的发病率为3.57% (占476名患者中的17名).
- 患有AD的患者表现出更大的输管深度,更高的血红蛋白水平,以及在ICU中显著延长的气管输管.
- 多变量逻辑回归确定了ICU中长时间的气管管道输液作为AD的独立风险因素 (P=0.013).
结论:
- 肝移植后AD的发病率高于以前报告的全身麻醉.
- 在ICU中长时间的气管管道输入是肝移植患者状腺突变的重要危险因素.
- 需要进一步的研究来阐明机制,并在这个高风险群体中制定AD的预防策略.
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