在中国人口中,新生儿Ca/P/Mg状态的变化趋势
Song Mao1, Liangxia Wu1, Wenjing Shi1
1Department of Pediatrics, Shanghai Sixth People's Hospital, Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Translational pediatrics
|October 10, 2023
概括
新生儿疾病与血清和水平降低有关. 新生儿的出生体重和前素 (PCT) 与这些矿物质水平有非线性关联.
科学领域:
- 新生儿医学 新生儿医学
- 生物化学 生物化学
- 儿科内分泌学 儿科内分泌学
背景情况:
- (Ca), (P) 和 (Mg) 对于维持新生儿平衡至关重要.
- 了解这些矿物质的血清含量对于新生儿健康评估至关重要.
研究的目的:
- 研究各种疾病的新生儿血清Ca,P和Mg水平的趋势和关联.
- 分析新生儿状况,出生体重和前素 (PCT) 与血清矿物质水平之间的关系.
主要方法:
- 追溯分析了82名早产新生儿,173名新生儿败血症患者,50名低血糖患者,254名黄患者,43名血溶性疾病患者和59名对照患者.
- 血清Ca/P/Mg水平按季度分析,并使用二进制逻辑回归来检查与疾病的关联.
- 使用平滑曲线和值效应分析评估了与出生体重和PCT的非线性关联.
主要成果:
- 新生儿疾病,包括溶血性疾病,低血糖症,败血症,黄和早产,与较低的血清Ca水平显著相关.
- 低血糖和早产与较低的血清P水平有显著的关联;Mg水平与任何疾病没有显著的关联.
- 在出生体重/PCT和血清Ca/P水平之间发现了显著的非线性关联,确定了转折点.
结论:
- 新生儿疾病与血清Ca和P水平的下降趋势有关.
- 出生体重和PCT与新生儿的血清Ca和P水平有显著的非线性关系.
相关概念视频
01:33Introduction to Electrolytes
10.3K
In humans, electrolytes play a vital role in various physiological processes. Balancing electrolyte levels is essential for normal body functions; their imbalance can be life-threatening. The major electrolytes include sodium, potassium, chloride, calcium, phosphate, and bicarbonate. They are primarily involved in physiological processes, such as nerve signal transmission, membrane trafficking, muscle contraction, buffering body fluids, and balancing water levels in the body.
Role of Sodium
One...
Role of Sodium
One...
10.3K
01:21Skeleton and Calcium Homeostasis
4.6K
Calcium is not only the most abundant mineral in bone but also the most abundant mineral in the human body. Calcium ions are needed for bone mineralization, tooth health, heart rate regulation and strength of contraction, blood coagulation, the contraction of smooth and skeletal muscle cells, and the regulation of nerve impulse conduction. The average calcium level in the blood is about 10 mg/dL. When the body cannot maintain this level, a person will experience hypo or hypercalcemia.
4.6K
01:27Roles of Electrolytes: Calcium and Phosphate
293
Calcium and phosphate are essential electrolytes in the human body, with calcium being the most abundant mineral. Around 99% of the body's calcium is stored in the skeleton and teeth, forming a crystal lattice of mineral salts in combination with phosphates. Calcium plays crucial roles in various bodily functions such as blood clotting, neurotransmitter release, muscle tone maintenance, and nervous and muscle tissue excitability.
The calcium concentration in blood plasma is primarily...
The calcium concentration in blood plasma is primarily...
293
01:31Essential Minerals for Bone Health
4.0K
The minerals contained in all of the food we consume are essential for our organ systems. However, certain essential minerals, such as calcium, phosphorus, magnesium, manganese, and fluoride, largely affect bone health.
Calcium and Phosphorus
Calcium is a critical component of bones, especially in the form of calcium phosphate and calcium carbonate. Since the body cannot make calcium, it must be obtained from the diet. However, calcium cannot be absorbed from the small intestine without...
Calcium and Phosphorus
Calcium is a critical component of bones, especially in the form of calcium phosphate and calcium carbonate. Since the body cannot make calcium, it must be obtained from the diet. However, calcium cannot be absorbed from the small intestine without...
4.0K
01:28Chronic Kidney Disease III: Interprofessional Care
24
Chronic kidney disease (CKD) requires collaborative and comprehensive management. CKD progresses through stages and can lead to end-stage kidney disease (ESKD) if untreated. Interprofessional collaboration and patient education are crucial, enabling patients to manage their health and improve their quality of life.Diagnostic approach for chronic kidney diseaseThe diagnosis of CKD primarily focuses on the glomerular filtration rate (GFR), which assesses kidney function by measuring how well...
24