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对双相情感障碍患者的性饮食的试点研究
Nicole Needham1, Iain H Campbell1, Helen Grossi2
1Centre for Clinical Brain Sciences, University of Edinburgh, UK.
BJPsych open
|October 10, 2023
概括
这项研究发现,招募和保留患有双相情感障碍的个体进行饮食干预是可行的. 大多数参与者在很少的轻微副作用下实现了症,支持进一步的研究.
科学领域:
- 营养精神病学 营养精神病学
- 代谢精神病学 代谢精神病学
- 临床营养学 临床营养学
背景情况:
- 新出现的病例报告表明,性饮食可能有利于双相情感障碍.
- 之前没有任何临床试验研究了双相情感障碍的性饮食.
研究的目的:
- 评估招募和留住参与者进行基因饮食干预在双相情感障碍中的可行性.
- 评估修改基因饮食在患有双相情感障碍的euthymic个体中的坚持和安全性.
主要方法:
- 一个6-8周的修改基因饮食干预措施被实施给双相情感障碍的euthymic个体.
- 评估了招聘,留住和坚持的情况.
- 监测了临床,经济和功能结果,包括每日血和葡萄糖水平.
主要成果:
- 观察到高招聘和保留率,27名参与者中有20人完成了6至8周的干预.
- 91%的参与者达到并维持了症,平均血水平为1.3 mmol/L.
- 大多数不良事件是轻微的和可控的,在接受SGLT2抑制剂的参与者中报告了一次严重事件.
结论:
- 对于患有双相情感障碍的euthymic个体来说,一种基因饮食干预是可行的.
- 高依从性和耐受性表明未来随机对照试验的潜力.
- 需要进一步的研究来证实它在治疗双相情感障碍方面的有效性.
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