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在患有败血症或败血性休克的重症患者中输血触发因素:一项前性研究

Mohd Mustahsin¹, Souvik Maitra², Rahul Kumar Anand²

¹Department of Emergency Medicine & Critical Care, Era's Lucknow Medical College, Lucknow, Uttar Pradesh; Department of Anaesthesiology, Pain Medicine & Critical Care, All India Institute of Medical Sciences, New Delhi, India.

The Indian journal of medical research

|October 10, 2023

概括

在重症败血症患者中,红细胞输血触发率低于7g/dL是常见的,并且似乎不会影响28天的死亡率. 需要对其他输血参数和长期结果进行进一步评估.

科学领域:

关键护理医学关键护理医学
血液学血液学血液学
输血医学输血医学

背景情况:

目前对重症败血症患者的输血触发实践缺乏明确性.
血红蛋白触发,红细胞年龄和输血量与死亡率之间的关联需要进一步调查.

研究的目的:

评估目前在重症败血症患者的输血触发实践.
评估血红蛋白触发和红细胞输血参数对死亡率和不良结果的影响.

主要方法:

一项前性研究包括108名危急性败血症患者 (18-70岁).
收集的数据包括基线人口统计,临床参数和输血细节 (血红蛋白触发量,红细胞年龄,输血单位).
测量结果是28天和90天的死亡率,机械通风持续时间,血管压缩剂治疗,ICU/住院和置换疗法.

主要成果:

输血的中位数触发器是6.9g/dL.
28天死亡率的预测因素包括APACHE II评分,累积液体平衡和入院血小板计数.
对于90天死亡率,预测因素是APACHE II评分,累积液体平衡和输血触发因素 (aOR:3 [1.07,8.34],P=0.035).

结论:

在危急性败血症患者中,目前的做法涉及低于7g/dL的输血触发器.
这种输血触发水平在研究人群中没有显著影响28天死亡率.

关键词:

输血输血输血输血输血输血输血在ICU中,医生会对患者进行治疗.红血细胞 (RBC) 是一种血液中的血球蛋白.死亡率死亡率这是一种血症.

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