儿童中神经发育,内化和外化障碍之间的累积并发症:网络方法
Oliver J Watkeys1,2, Kirstie O'Hare1, Kimberlie Dean1,3
1School of Clinical Medicine, Discipline of Psychiatry and Mental Health, Faculty of Medicine and Health, University of New South Wales (UNSW), Level 1, AGSM Building, Kensington Campus, Sydney, Australia.
儿童精神障碍往往同时发生. 网络分析显示,发育和情绪障碍是共患病模式的核心,在儿童中观察到明显的内化和外化集群.
科学领域:
- 儿童和青少年精神病学 儿童和青少年精神病学
- 发展心理学 发展心理学
- 网络科学 网络科学
背景情况:
- 精神疾病的累积并发症在成年人中被认可,但儿童时期的模式仍然不清楚.
- 了解儿童并发症对于早期干预和有效的治疗策略至关重要.
研究的目的:
- 调查12岁以下儿童累积精神障碍并发症的新兴模式.
- 利用网络分析来绘制童年不同精神障碍之间的关联.
主要方法:
- 对2002-2005年间出生的澳大利亚儿童的一大纵向队列 (n=90,269) 的分析.
- 对八种精神障碍类型的诊断进行了网络分析,这些诊断来自12岁以下的行政健康记录.
- 评估条件关联和网络结构,包括模块化和中央节点.
主要成果:
- 2.5%的儿童在12岁时至少患有一种精神障碍;其中20.3%患有两个或两个以上的精神障碍.
- 所有分析的精神障碍都在网络中相互连接.
- 童年情感,情感和发育障碍成为最核心的疾病,与其他疾病联系在一起. 两个群体 (内部化/外部化和神经发育/睡眠障碍) 被弱确定.
- 在并发症网络结构中观察到显著的性别差异.
结论:
- 发育和儿童情感/情感障碍在儿童精神障碍并发症中起着关键作用.
- 这些中心疾病可能有共同的症状,促进与其他疾病的联系.
- 网络分析为儿童精神病理学的复杂结构提供了有价值的见解,并突出了潜在的干预目标.
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