重植与移植:我们站在哪里?
Lindsay E Janes1, Christine McAndrew1, L Scott Levin2
1Department of Orthopaedic Surgery, University of Pennsylvania, 3737 Market Street, Philadelphia, PA, 191904, USA.
概括
手部移植提供了与再移植相似的结果,可以显著改善截肢患者的生活质量. 虽然存在风险,但知情的患者可能会发现它是肢体损失恢复的可行选择.
科学领域:
- 重建性微手术是重建性的微手术.
- 移植免疫学 移植免疫学
- 创伤外科 手术 创伤外科
背景情况:
- 创伤性截肢在肢体护理中存在持续的挑战,通常会导致持久的残疾.
- 重植和先进的假肢并不总能恢复完整的功能,因此需要寻找替代解决方案.
- 上肢损失显著影响患者的生活质量和功能独立.
研究的目的:
- 为手和重建外科医生提供当前上肢移植的概述.
- 为了让外科医生能够更好地为截肢患者提供移植作为治疗选择的建议.
- 突出手部移植对肢体损失的潜在好处和考虑因素.
主要方法:
- 关于上肢移植和再移植的当前文献的全面审查.
- 分析国际注册机构关于手部和复合组织移植的数据.
- 对再种植和移植程序的结果的综合.
主要成果:
- 重植和移植后的感觉和功能结果是可比的.
- 手部移植中与免疫抑制相关的并发症与其他固体器官移植中的并发症相似.
- 手部移植的财务成本很大,但与使用假肢的长期费用相美.
结论:
- 手移植可以大大提高患者报告的结果和生活质量,在精心挑选和知情的个体.
- 免疫抑制风险是一个关键因素,需要对患者进行彻底的教育和考虑.
- 尽管面临挑战,手部移植在管理上肢损失方面取得了重大进展.
相关概念视频
Tissue Transplantation
380
Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...
380
Introduction to Nuclear Reprogramming
1.9K
Nuclear reprogramming is the process of switching gene expression of one cell type to that of another cell type, usually from a differentiated cell state to an undifferentiated cell state. Differentiation occurs during processes such as development and morphogenesis, tissue regeneration, and malignancy. Cells can also be artificially induced to reprogram their gene expression by techniques such as nuclear transfer, induced pluripotency, and cell fusion. Such techniques have many applications in...
1.9K
Bone Marrow Sampling and Transplants
342
Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy...
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy...
342
Plant Tissue Culture
38.0K
Plant tissue culture is widely used in both primary and applied science. Applications range from plant development studies to functional gene studies, crop improvement, commercial micropropagation, virus elimination, and conservation of rare species.
38.0K


